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hair lossIn an independent study, Relevant Research, Inc. determined that 40% of men experience noticeable hair loss by the age of 35. By age 60, 65% of men will suffer from balding or thinning hair. For some men, the problem begins at an even younger age, as early as their 20s.

The Mayo Clinic reports that the genetic condition commonly called male (or female) pattern baldness is the most common cause of hair loss. Men in particular are genetically predisposed to lose their hair as they age, thanks to a sensitivity to certain sex hormones, including testosterone. These hormones are collectively called androgens.

Over time, these hormones cause hair follicles to shrink, resulting in thinner and thinner hair. Eventually, the follicles stop growing hair altogether.

What is Male Pattern Baldness

Known in the medical world as androgenic alopecia, male pattern baldness affects a majority of adult men at some point in their lives. The most common symptom of male pattern baldness is a receding hairline, especially at the temples and on the top of the head. This is commonly called a “bald spot”, but is known as vertex balding in scientific circles. For women who suffer from female pattern baldness, the condition manifests as patches of thinning hair scattered around the top of the scalp.

Regardless of gender, the cause of these patches of thin hair or bald spots are caused by the miniaturization of hair follicles. Over time, androgens cause hair follicles to literally get smaller and less able to produce hair.

The mechanism by which this occurs is complicated. An enzyme known as 5 Alpha Reductase occurs naturally in our bodies, and converts testosterone into the hormone dihydrotestosterone, or DHT. High levels of DHT are the direct cause of hair follicle shrinkage and premature shedding of hair. DHT attaches to our hair follicles and causes them to begin producing smaller, finer hairs, and ultimately stop producing hair entirely.

The Foundation of Hair Restoration has identified three major factors in androgenic alopecia (male or female pattern baldness).

  1. Genetic Predisposition – Androgenic alopecia is a genetic condition, and is passed down from parent to child. The gene can express whether it is acquired from the mother, father, or both.
  2. DHT – Dihydrotestosterone is the direct cause of male or female pattern baldness. High levels of the hormone are a strong indicator that baldness will occur.
  3. Age – As both men and women age, they become more susceptible to the shrinking of hair follicles, causing baldness.

What Causes Male or Female Pattern Baldness

A number of other factors can contribute to the likelihood of baldness. Everything from lifestyle to nutrition, as well as certain diseases, can be the “final straw” that causes male or female pattern baldness symptoms to present.

  • Androgenic Alopecia – This is the genetic condition that is the cause of 95% of male pattern baldness, as well as female pattern baldness to a lesser extent.
  • Nutrition – Complete baldness is actually comparatively rare. Thin hair and bald spots are far more common, but poor nutrition can intensify the condition into near-total hair loss. Caloric deficiency (not eating enough), as well as deficiencies in certain vitamins and minerals have the strongest correlation to baldness. Nutrients important to hair include biotin, amino acids, zinc and iron. Finally, eating excessive amounts of animal fats on a regular basis can accelerate hair loss.
  • Stress – Stress is bad for our health in many ways, including bringing on hair loss. Studies have shown that stress restricts the supply of blood to our capillaries, preventing oxygen and other nutrients from reaching hair follicles. This damages the follicles over time, preventing hair growth.
  • Medications – Certain medications, especially ones that affect hormone levels, can cause hair loss as a side effect. The most common drugs that have this type of effect are contraceptive pills, anabolic steroids, some hormone replacement treatments, and acne medication. Some drugs used for blood pressure, cholesterol, heart disease, and diabetes can also contribute to baldness.

Treatment of Androgenic Alopecia

There are two medications currently approved by the FDA for use in treating androgenic alopecia by stopping or reversing the shrinkage of hair follicles.

  • Finasteride (commonly sold as Propecia) – Finasteride is a prescription drug taken in pill form for the treatment of male pattern baldness. By reducing the levels of DHT in the body, it can be effective in stopping hair follicles from shrinking. Finasteride is approved for men only, and is not indicated for use by women. The drug does list multiple unpleasant side effects such as loss of libido, hypogonadism, erectile dysfunction, sexual dysfunction, and gynecomastia.
  • Minoxidil – This topical treatment has been sold over the counter since the 1990s, and is safe for use by both men and women. Minoxidil increases the flow of blood to hair follicles, making it effective in halting the early symptoms of androgenic alopecia.
  • Minoxidil fortified with finasteride – This combination of the two drugs is typically used as a long-term maintenance regimen to keep baldness from occurring or returning after stopping treatment with oral finasteride. Due to the side effects associated with the oral finasteride, it is generally not advisable to take it longer than strictly necessary. By mixing finasteride with minoxidil as a topical treatment, most of the side effects are mitigated.

Treatment of General Symptoms of Hair Loss

There are also other drugs and medications intended to prevent or reverse loss of hair from other causes. These medications are prescription drugs, applied topically. Consult with a medical professional to determine which treatment is best for your situation, and to obtain a prescription.

  • Ketoconazole – Developed as an anti-fungal medication, ketoconazole is also effective in reversing the effects of androgenic alopecia. The drug counters the effects of dihydrotestosterone, the hormone that directly causes male and female pattern baldness. This hormone binds to hair follicles, shrinking them and causing them to grow thinner hair, or no hair at all.
  • Spironolactone – Specifically developed for female pattern baldness, spironolactone is taken in tablet form and works to lower testosterone produced in the adrenal glands and ovaries. The drug also reduces water retention, and can be applied as a topical scalp solution, although to lesser effect. This is a good alternative to finasteride, to avoid its side effects.
  • Azelaic Acid – Naturally found in whole grains, azelaic acid has antibiotic properties and can destroy harmful skin bacteria. It also targets 5 Alpha Reductase, the hormone that converts testosterone into DHT. As DHT is the primary cause of androgenic alopecia, this is another great alternative to finasteride.

There are so many treatments and management regimens for baldness that is can be next to impossible for the layman to select the right one. Most of the medications listed here are prescription, and consulting with a medical professional is always the best first step in managing male or female pattern baldness. The problem of keeping hair on one’s head has been on people’s minds for many, many years. Fortunately, modern medicine is finally starting to catch up to the issue. Countering male or female pattern baldness is well within reach for most people these days. Visit your medical professional to learn about the options for your case.

Causes and Modern Treatments for Hair Loss

Saleamp Design April 8th, 2016

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DHEADehydroepiandrosterone (DHEA) is a naturally occurring hormone produced in the body. Secreted by the adrenal glands, it is precursor to other hormones and is transformed by the body into specific hormones once it reaches the target tissue. As a prohormone, most of it effects are related to its end products as opposed to DHEA itself. 

DHEA is gaining traction as an anti-aging supplement. It is also being explored as a treatment for several of the health conditions associated with aging. 

DHEA and its effects

DHEA is often touted as a “youth restoring” hormone because of its reputation for slowing down the age process, improving general energy levels and cognitive skills.  Because of this, many see it as a solution to regulate the side effects of aging and hormone depletion.

DHEA supplementation has shown an increase in energy, cognitive concentration, greater muscle mass/retention and slowing down the progression of Alzheimer disease. DHEA has been shown to have an influence on erectile dysfunction and lack of sex drive. In addition, Men with low DHEA more often experience depression as well as higher risks for overall mortality, including heart failure and cardiovascular threats.

DHEA Decline with Age

Unfortunately, DHEA production declines as its importance increases. DHEA production reaches its highest point during the 20s, but as one grows older, the body’s DHEA production  decreases, leaving as little as 20% of the healthy output by the time one reaches 70.

Since it is a precursor to other hormones, this decline leads to a corresponding effect in other hormones as well. Estrogen and testosterone synthesis, in particular, wane once the DHEA levels decrease. This brings forth several consequences for both sexes. In men, specifically, age-related DHEA decrease leads to a decline in testosterone secretion. This decline is compounded because of the larger role DHEA plays in the production of testosterone as we age.

DHEA Supplements and their Effects

From trials, DHEA supplements have been shown to increase muscle mass, strength and physical well-being in general. In addition, tests of increased concentration, in men and women, have been shown to improve sexual potency and mood, with women experiencing less menopausal symptoms after taking supplements. Overall, DHEA has been seen as an anti-aging supplement, providing bone and muscle strength, better moods and immune system and increased memory. 

When tested on patients with diabetes and neurological disorders, DHEA was not seen to improve erectile function and potency in patients. It has also been shown to exhibit minimal side effects such as mild acne, swollen ankles and increased facial hair in some women.

The effect of long term treatment on cardiovascular conditions and hormone-dependent tumors has not yet been studied, or have yielded conclusive results. 

DHEA Frontiers

DHEA supplements for anti-aging purposes are currently gaining traction. As a precursory hormone, it is seen by many as a way to regulate hormone balance within the body. In addition, DHEA’s reputation in increased bone and muscle strength, as well as energy, has many physicians exploring DHEA supplements and its effect on bone growth, depression, and other mood and cognitive disorders.

Hormone Therapeutics

Hormone Therapeutics specializes in endocrine and hormone-related treatment, and is committed to finding the best treatment for your well-being.  If you’re curious about how DHEA supplements can improve you and your life, Hormone Therapeutics can provide the answers for you. Call us today!

Do You Need Help?

Hormone Therapeutics is the leading national company assisting men who want to get their lives back through Hormone Replacement and Testosterone Replacement therapy. Our local physicians are ready to treat you anywhere in the entire country. Hormone Therapeutics is pioneering an easier, cost efficient and more private way for you to work with our clinical advisors and physicians from the privacy of your home or office after your local physical exam confirms you have one of the symptoms of Low T.

Contact us today and our clinical advisors will work with you on a hormone therapy program that may include prescribed hormones, exercise, nutrition and sleep programs to reclaim your vitality.

 

 

DHEA Benefits and Frontiers

Saleamp Design April 1st, 2016

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Depression from Low Testosterone and EstrogenA recent study at the George Washington University, found that men diagnosed with borderline low testosterone levels had much higher rates of experiencing depression and depressive symptoms compared to the general population. In the study, 56% of the male participants were diagnosed with depression while 25% were already taking medications for this.

Produced in the testicles, testosterone helps drive a man’s production of sperm, muscle strength and mass, sex drive, facial and body hair and bone density.  Men who don’t produce the normal amount of testosterone may have a condition called hypogonadism.

To Ward off Depression, Testosterone Converts to Estrogen

Testosterone, the male sex hormone, seems to have anti-depressant like properties, yet the exact mechanism of its effect still remained unclear.

In 2012, Mohammed Kabbaj and Nicole Carrier, both researchers at the Florida State University College of Medicine, are working to elucidate such mechanisms.  They have found out that a particular pathway called MAPK pathway in the hippocampal region, a part of the brain, involved in regulation of stress responses and memory formation, plays a vital role in mediating the effect of testosterone.

Low Testosterone and Depression

Between men and women, females are typically more prone to suffer from depression, however, men diagnosed with low T or hypogonadism are also predisposed to depression or anxiety. Fortunately, hormone replacement therapy has been found to effectively enhance mood.

While it may seem that much is already known, it’s still very important to fully understand where and how these effects are happening so that scientists can develop better, targeted antidepressant therapies.

In the study, Kabbaj performed several experiments in neutered male rats and found that the rats manifested depressive-like behaviors that were then reversed by supplemental testosterone replacement.

According to the researcher, in order to protect males with hypogonadism from developing depression, testosterone in the brain must be converted to estrogen. Kabbaj stated a certain brain enzyme ‘mediates’ the conversion of testosterone to estrogen. Furthermore, inhibiting such enzyme in the hippocampal area has prevented the antidepressant effect of testosterone.  This makes the conversion to estrogen vital.

In this study, the antidepressant effect of supplementing low testosterone to normal levels has only manifested in male rats, not in female rats.

 

Do You Need Help?

Hormone Therapeutics is the leading national company assisting men who want to get their lives back through Hormone Replacement and Testosterone Replacement therapy. Our local physicians are ready to treat you anywhere in the entire country. Hormone Therapeutics is pioneering an easier, cost efficient and more private way for you to work with our clinical advisors and physicians from the privacy of your home or office after your local physical exam confirms you have one of the symptoms of Low T.

Contact us today and our clinical advisors will work with you on a hormone therapy program that may include prescribed hormones, exercise, nutrition and sleep programs to reclaim your vitality.

 

Revealed: How Testosterone Converts to Estrogen to Battle Depression

Saleamp Design March 29th, 2016

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We see so many mistakes on the message boards and have so many people come to us for help following a litany of errors. The Top Testosterone mistakes have a multitude of consequences from health risks, to side effects, to quality of life impairment to abandoning programs. There is one commonality, however, though in most of the mistakes. The patients are not getting proper guidance and oversight from a HRT specialized physician. Some mistakes seriously impacted their quality of life, or resulted in men stopping testosterone prematurely.

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Top Testosterone Replacement Therapy Mistakes

Saleamp Design March 16th, 2015

Posted In: Low T Info, Testosterone Therapy, Uncategorized

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