What You Need to Know about Testosterone Injection Protocol
Many guys find testosterone injection intimidating, perhaps because there isn’t enough information about it to get started. Men ask for complete details and for that, below is a brief discussion on what you need to know about TRT when getting started.
Testosterone Injection Protocol
- 1.0 mg Arimidex (Anastrozole) per week in divided doses
- 250 IU Human Chorionic Gonadotropic injected subcutaneously every other day
- 100 mg testosterone enanthate or cypionate given per week, could be two or more depending on doctor’s advise
Testosterone injection done once a week causes spikes in the level of testosterone followed by lows. This can make you feel worse by the end of the end compared to your pre-TRT stare. Later on, the dead zone gets broader, feeling no relief with testosterone injection. This makes injecting twice a week or every other day (EOD) much better.
When you have frequent injections, the volumes are too small, using #29 0.5ml 50IU insulin syringes. You can inject in the muscle at the side of your thighs (vastus lateralis). The injection loads very slowly, however, the tiny plunger causes very high pressures. Never use 1.0ml syringes. The same size of syringe can be used for HCG injections.
Small needles cause less muscle damage. Some use #25 needle but this may not be faster compared to 50IU insulin needles. A clinical research has found that testosterone injection through subcutaneous tissue, which is under the skin into the body fat, provide a steadier levels of testosterone and enhances sense of well-being.
For men who exercise, sweat or shower a lot, transdermal testosterone gels and creams are not advised. Transdermal creams and patches are quite hefty and about 10 percent only of its testosterone content is absorbed. Also, men who have low levels of thyroid hormones don’t efficiently absorb testosterone administered topically.
Some people absorbs transdermal creams at the beginning, however, changes in the skin can prevent absorption after some time. With testosterone injections. There are no uncertainties or limitations when it comes to delivery of the drug.
Guidelines on hCG Injection
Human Chorionic Gonadotropin (hCG) is a water-based peptide hormone that is injected to replenish lost luteinizing hormone (LH) that TRT suppresses. A lack of hCG can result to deactivation of LH receptors present in the testes. This results in:
- Shrinkage of testes. For some, the testes can eventually lead to testicular atrophy. The degree of shrinking differs from person to person, but is more common among older men.
- Fertility can be greatly affected. If you want an offspring, hCG injection is necessary. If not given, it may greatly reduce fertility or you may not recover fertility.
- Less pain sensation. When the testes shrinks, some men feel pain in their testes. You can avoid this situation by injecting hCG.
- When there’s a huge dearth of hCG and LH, the scrotum shrinks too and pull up to the body, giving the pre-pubescent appearance. This isn’t good for a person’s body image perception, and may also affect how women see you sexually.
- Promotes pregnenolone production. Testes are the major producer of the hormone pregnenolone – a precursor to all steroid hormones such as cortisol, testosterone, DHEA, estrogen among other. It is also vital for proper mental functioning. hCG injection prevents a drug-induced deficiency of pregnenolone. People who are on TRT without hCG and then just start hCG reported a significant improvement on their mood, that most attributed to increase in pregnenolone levels.
When you inject hCG, you administer it into the fat beneath the skin the same as diabetics administer insulin. Research on the use of subcutaneous injection in men has showed the effectiveness of 250IU EOD dose. You can look for diabetes patient education material on how to administer insulin injection to be used for testosterone injection or hCG.
Guidelines on Anastrazole and Aromotase Inhibitors
Elevated serum estradiol/E2 (30pg/ml and above) can interfere many benefits of testosterone injection. A serum estradiol equivalent to 22pg/ml is near optimal and to be able to get near this level, a person should take Anastrozole. Many men who began with TRT experienced favourable results that later on faded as estrogen levels increase.
My advice is to begin Anastrozole at 1.0mg per week in divided doses beginning at the day of your first injection. Then follow up estrogen lab tests for any necessary Anastrozole dose adjustments. It is not a good idea to wait and check if your estrogen levels increase before taking action. Take Anastrozole EOD if possible.
Testosterone injection with a dose of 100mg should result in 800 to 900 total testosterone (TT) range. While this is a good result, monitor your free testosterone (FT) or the bio-available testosterone. Some doctors won’t bother looking at the TT numbers at all. With age, SHBG (Sex hormone-binding globulin) levels increase while FT levels decrease.
See, a TT of 1000 of a young man won’t be the same as the TT of 1000 for an older man with high SHBG levels, because the FT level of the older man will likewise be well below, even though they have the same TT. Lab ranges presented on lab reports are age-adjusted.
Further, you have to know about prostate-specific antigen (PSA), problems in the prostate and digital rectal exam. Estrogen is a major factor of enlarged prostate or BPH (Benign prostatic hyperplasia). Many find that decreasing estrogen to 22pg/ml improves their urine flow as well as BPH. You also have to monitor your haematocrit levels as part of routine lab work.
Hormone Therapeutics Testosterone Therapy
Being a leading provider of low testosterone therapy solutions, we are always looking for newer ways to improve blood testosterone levels for our patients. We believe on improving testosterone levels with not only different testosterone treatment options that we offer, but also with diet, exercise, and therapeutic methods. Over the years, we have seen that our patients have greatly benefited from our Low-T therapy and treatment solutions, and our network of patients have grown across across all major cities of United States, including: Los Angeles, Houston, Miami, Chicago, Jersey City, and Seattle.
If you or a loved one is dealing with low blood testosterone levels, contact us today to get a free evaluation of your Low-T symptoms and see how our treatment options can help you with your low testosterone.
Sign up today and Get our ebook, ‘Naturally Increase Your Testosterone Levels’ absolutely FREE.
What You Need to Know about Testosterone Injection Protocol
Saleamp Design January 17th, 2017
Posted In: Testosterone Therapy
Tags: anastrozole, aromatase inhibitors, free testosterone, HCG, Human Chorionic Gonadotropin, LH, Luteinizing Hormone, pregnenolone, prostate-specific antigen, serum estradiol, testicular atrophy, testosterone, Testosterone Enanthate, testosterone injection, Total Testosterone, TRT, TRT protocol
How does Testosterone Affect Sexual Health?
Can testosterone improve sexual health?
Many factors fuel the sexual health of men as well as their sexual performance, ability to perform and changes in their ability to function as they once could. Low testosterone plays a significant factor in all of these and treating Low T can improve interest in sex, sexual function and sexual performance.
The Effects of Low T on Sexual Health
While we do understand that testosterone production comes from a healthy HPA Axis, or communication between your Hypothalamus, Pituitary Glands, Adrenals and Testicles, science still does not understand exactly how testosterone improves sexual health or performance. As you probably noticed in High School, College or amongst your friends, there is no normal level of sexual interest amongst men or women.
Like your testosterone levels, it peaks around 19 and usually slowly declines for the rest of your life. Each person takes a different path, however, and declining sexual interest is typically tied to declining testosterone levels. These levels can follow a steady decline, or can be accelerated by health issues, stress, poor sleep and even by keeping sexually active. Many men can lose sexual interest at normal testosterone levels or maintain sexual health even at low testosterone levels but as testosterone levels get depleted it will universally effect sexual interest and performance.
One study of Men in the NE of the US showed 11% of men had a lack of sex drive. The researchers also found 28% of men with low testosterone levels had a low libido which means that men with low testosterone levels were 256% more likely to have low sex drive or low libido. The average age of the study participants was 47.
Low Testosterone and Erectile Dysfunction
Erectile Dysfunction, or ED, can be caused by many health problems including low testosterone, atherosclerosis (hardening of the arteries), diabetes, high blood pressure and high cholesterol. Those last three items all cause hardening of the arteries. If they are damaged, the penis has difficulty dilating and bringing sufficient blood flow required for an erection. Testosterone therapy can lead to increased libido and interaction and connection between the brain and penis.
Viagra is an example of an oral PDE5 inhibitors that encourage an increase in nitric oxide which dilates the blood vessels and encourages more blood flow to the penis. Three potent selective PDE5 inhibitors (sildenafil (Viagra; Pfizer), tadalafil (Cialis; Lilly), and vardenafil (Levitra; Bayer)) are currently available. Testosterone therapy will often increase the libido and sexual function to erase Erectile Dysfunction, but often our physicians will prescribe a combination with PDE5 inhibitors as well.
Studies are showing that men with classic hypogonadism, or low testosterone, have a reduced response to PDE5 inhibitors and see a significant response improvement with Testosterone Therapy. For patients who fail to see ED improvement following TRT and PDE5 inhibitors we can prescribe and test the direct injectable Trimix.
The Connection of Testosterone Levels and Sexual Health
While this sounds like a juvenile sex joke, we are now seeing that lowered testosterone levels lead to a decreased sex life, but that a decreased sex life also can lower ones testosterone levels in a study at the University of Sydney in Australia.
Researchers followed 1,700 men over the age of 70. The study asked questions and measured a number of things. The study tracked the ability to keep and maintain an erection. It measured the frequency that sexual activity led to ejaculation (through masturbation or sexual intercourse). The study also tracked libido and sexual health versus earlier times in their lives.
During the study, all of the men had blood tests regularly taken and the following tests measured: Total Testosterone, Free Testosterone, Estrogen, SHGB and some other hormones.
Researchers discovered a 10% reduction in testosterone levels led to a noticeable decrease in sexual activity but no change in the number of erections. Another study showed that testosterone levels increased on night after sexual activity without any increase on nights where there was no sexual activity. Physicians are concerned that a lack of sexual activity can accelerate low testosterone.
A further study showed that men taking Cialis had higher testosterone levels than men taking Viagra. Both drugs are PDE5 inhibitors to boost nitric oxide and blood flow to the penis. Cialis, however, last 36 hours for most people rather than 6-8 hours. Cialis users typically have more intercourse over this extended time period.
The researchers concluded that “as it is unlikely that the two drugs have a different direct effect on the pituitary-testis axis, this effect is probably due to the higher frequency of full sexual intercourse.”
A Chinese study observed a group of men that abstained from ejaculation for one week and had their testosterone levels tested each day. Research showed that abstaining for 6 days had no effect on testosterone levels, however, on the seventh day the testosterone levels surged to 145.7% of the baseline then plummeted on the 8th day.
The researchers believe the testosterone surge was the result of a negative feedback suppression of Luteinizing hormone (LH secretion) which is essential for testosterone production.
Hormone Therapeutics aims to help people looking to improve and optimize their health through natural means or through the guidance of our physicians.
Don’t miss out our free weekly tips and news on Low T, hormone balancing, healthy living, nutrition and a lot more.
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How does Testosterone Affect Sexual Health?
Saleamp Design November 15th, 2016
Posted In: Low T Info
Tags: atherosclerosis, Bayer, blood flow, boner, Cialis, diabetes, dilates, ED, erectile dysfunction, erection, high blood pressure, high cholesterol, hypogonadism, inhibitors, intercourse, Levitra, LH, LH secretion, libido, Lilly, Lutenizing hormone, nitric oxide, PDE5, PDE5 inhibitors, penis, Pfizer, pituitary, sex drive, sexual health, sexual performance, sildenafil, tadalafil, testes, testicles, testosterone level, testosterone therapy, trimix, TRT, vardenafil, Viagra
Here’s What You Should Know about Testosterone Production
Testosterone is important as it maintains our physical strength, our focus, and our mood, but do you an idea about testosterone production? How is it made?
It’s not just an academic question. An understanding of how our bodies produce testosterone leads to an understanding of what might cause our bodies to stop producing enough of the stuff, and understanding a problem is the first step to solving it.
Testosterone Production 101 – The Three Types of Testosterone
In essence, testosterone is a steroid hormone. The changes and benefits it triggers in the body are detailed right over here. The average male human creates 7mg of testosterone per day, but there are actually three different types. Not all of it is usable by the body, or at least not to produce the effects you’re probably looking for.
Free Testosterone
Free testosterone is so named because it has no attached proteins. It’s free to float through the bloodstream, and isn’t bonded to any other molecules. Free testosterone is the type of testosterone that has all those great physical and mental benefits, because it’s able to roam our bodies and activate receptors in various cells. Even though this is the kind of testosterone we think of as the most beneficial, it has the smallest concentration of the three. It only comprises about 2%-3% of our total testosterone levels. Everything we do for testosterone production is really meant to increase free testosterone, but the best way to do that is to raise our overall levels.
SHBG-Bound Testosterone
This type of the male hormone makes up about 40%-50% of our total testosterone levels. It’s bound to SHBG (sex hormone-binding-globulin), which is a protein produced in the liver. It regulates the amount of free testosterone in the body. SHBG-Bound Testosterone is what’s known as “biologically inactive”, meaning it doesn’t actually have any other effect in our bodies beyond helping regulate our total levels. This type of T doesn’t have harmful effects either, but it is why a man might test with adequately high testosterone levels but still experience the symptoms of testosterone deficiency.
Albumin-Bound Testosterone
This makes up the remainder of our total testosterone. It’s bound to the protein albumin, which is also produced in the liver. Its function is to stabilize fluid volumes between our cells. Albumin-Bound Testosterone is also biologically inactive, but unlike the SHBG-Bound variety, its bond can be broken. That converts it back into free testosterone, making the stuff sort of testosterone reserve supply.
About 95% of our testosterone is produced in the testicles. The rest is made in our adrenal glands, which is why the hormone is present in women as well. For men, though, it’s almost entirely the testicles.
It’s a pretty complex process that results in the male hormone. Learn about testosterone production in this basic rundown:
The hypothalamus (part of the brain) secretes gonadotropin-releasing hormone. This stuff loops around to the back of the brain and hits the pituitary gland.
The pituitary gland receives the gonadotropin-releasing hormone, and responds by producing two more hormones. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Both of these natural chemicals enter the bloodstream and make their way to the testicles.
Once they’ve arrived down there, the FSH and LH do two different things. FSH initiates sperm production (important!), while LH kicks off testosterone production (just as important!)
The actual cells that create the testosterone are called Leydig cells. They work by converting cholesterol into testosterone. That cholesterol literally comes from the bloodstream, which is why a healthy level of T can actually improve your heart health. It’s also the reason eating eggs is so beneficial to testosterone levels!
During testosterone production, it’s released by the testicles into the bloodstream. Most of the stuff attaches to SHBG and albumin, nullifying its effects. It’s the small amount that remains free that aids our strength, focus, sexual drive, and all the other great benefits of testosterone.
Here’s a handy chart of the HPA-axis:
Image source: Wikipedia
In essence, testosterone is a steroid hormone. The changes and benefits it triggers in the body are detailed right over here. The average male human creates 7mg of testosterone per day, but there are actually three different types. Not all of it is usable by the body, or at least not to produce the effects you’re probably looking for.
Hormone Therapeutics aims to help people looking to improve and optimize their health through natural means or through the guidance of our physicians.
Don’t miss out our free weekly tips and news on Low T, hormone balancing, healthy living, nutrition and a lot more.
Want more?
Sign up today and Get our ebook, ‘Naturally Increase Your Testosterone Levels’ absolutely FREE.
Here’s What You Should Know about Testosterone Production
Saleamp Design November 4th, 2016
Posted In: Low T Info
Tags: albumin, biologically available, Follicle Stimulating Hormone, free testosterone, FSH, GnRH, growth hormone, HPA axis, hypothalamus, LH, low t, Luteinizing Hormone, pituitary, sex hormone-binding-globulin, SHBG, testicles, testosterone, testosterone levels, testosterone production
