This Swedish study tested the hypothesis that serum total testosterone and sex hormone-binding globulin (SHBG) levels predict cardiovascular events in elderly men. The study found that supplementing, and maintaining, testosterone reduces cardiovascular risks when the levels were maintained above 550ng/dl. This study also tested Estradiol levels, which was lacking from the previous studies. The study also found negative correlation between testosterone levels are type 2 diabetes risk. This Swedish study was compiled over 5 years and analyzed all kinds of markers, including SHBG.
The details of the study are included here:
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