Many guys find testosterone injection intimidating, perhaps because there isn’t enough information about it to get started. Men ask for complete details and for that, below is a brief discussion on what you need to know about TRT when getting started.
Testosterone injection done once a week causes spikes in the level of testosterone followed by lows. This can make you feel worse by the end of the end compared to your pre-TRT stare. Later on, the dead zone gets broader, feeling no relief with testosterone injection. This makes injecting twice a week or every other day (EOD) much better.
When you have frequent injections, the volumes are too small, using #29 0.5ml 50IU insulin syringes. You can inject in the muscle at the side of your thighs (vastus lateralis). The injection loads very slowly, however, the tiny plunger causes very high pressures. Never use 1.0ml syringes. The same size of syringe can be used for HCG injections.
Small needles cause less muscle damage. Some use #25 needle but this may not be faster compared to 50IU insulin needles. A clinical research has found that testosterone injection through subcutaneous tissue, which is under the skin into the body fat, provide a steadier levels of testosterone and enhances sense of well-being.
For men who exercise, sweat or shower a lot, transdermal testosterone gels and creams are not advised. Transdermal creams and patches are quite hefty and about 10 percent only of its testosterone content is absorbed. Also, men who have low levels of thyroid hormones don’t efficiently absorb testosterone administered topically.
Some people absorbs transdermal creams at the beginning, however, changes in the skin can prevent absorption after some time. With testosterone injections. There are no uncertainties or limitations when it comes to delivery of the drug.
Human Chorionic Gonadotropin (hCG) is a water-based peptide hormone that is injected to replenish lost luteinizing hormone (LH) that TRT suppresses. A lack of hCG can result to deactivation of LH receptors present in the testes. This results in:
When you inject hCG, you administer it into the fat beneath the skin the same as diabetics administer insulin. Research on the use of subcutaneous injection in men has showed the effectiveness of 250IU EOD dose. You can look for diabetes patient education material on how to administer insulin injection to be used for testosterone injection or hCG.
Elevated serum estradiol/E2 (30pg/ml and above) can interfere many benefits of testosterone injection. A serum estradiol equivalent to 22pg/ml is near optimal and to be able to get near this level, a person should take Anastrozole. Many men who began with TRT experienced favourable results that later on faded as estrogen levels increase.
My advice is to begin Anastrozole at 1.0mg per week in divided doses beginning at the day of your first injection. Then follow up estrogen lab tests for any necessary Anastrozole dose adjustments. It is not a good idea to wait and check if your estrogen levels increase before taking action. Take Anastrozole EOD if possible.
Testosterone injection with a dose of 100mg should result in 800 to 900 total testosterone (TT) range. While this is a good result, monitor your free testosterone (FT) or the bio-available testosterone. Some doctors won’t bother looking at the TT numbers at all. With age, SHBG (Sex hormone-binding globulin) levels increase while FT levels decrease.
See, a TT of 1000 of a young man won’t be the same as the TT of 1000 for an older man with high SHBG levels, because the FT level of the older man will likewise be well below, even though they have the same TT. Lab ranges presented on lab reports are age-adjusted.
Further, you have to know about prostate-specific antigen (PSA), problems in the prostate and digital rectal exam. Estrogen is a major factor of enlarged prostate or BPH (Benign prostatic hyperplasia). Many find that decreasing estrogen to 22pg/ml improves their urine flow as well as BPH. You also have to monitor your haematocrit levels as part of routine lab work.
Being a leading provider of low testosterone therapy solutions, we are always looking for newer ways to improve blood testosterone levels for our patients. We believe on improving testosterone levels with not only different testosterone treatment options that we offer, but also with diet, exercise, and therapeutic methods. Over the years, we have seen that our patients have greatly benefited from our Low-T therapy and treatment solutions, and our network of patients have grown across across all major cities of United States, including: Los Angeles, Houston, Miami, Chicago, Jersey City, and Seattle.
If you or a loved one is dealing with low blood testosterone levels, contact us today to get a free evaluation of your Low-T symptoms and see how our treatment options can help you with your low testosterone.
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Saleamp Design January 17th, 2017
Posted In: Testosterone Therapy
Tags: anastrozole, aromatase inhibitors, free testosterone, HCG, Human Chorionic Gonadotropin, LH, Luteinizing Hormone, pregnenolone, prostate-specific antigen, serum estradiol, testicular atrophy, testosterone, Testosterone Enanthate, testosterone injection, Total Testosterone, TRT, TRT protocol
Human Chorionic Gonadotropin is the glycoprotein hormone that mimics luteinizing hormone, a hormone produced by pregnant women by a growing embryo right after conception. The action of HCG is to prevent the disruption of corpus luteum in the ovary and to maintain the production of progesterone, another important hormone during pregnancy. HCG does a key role in the development of egg in the ovary and triggers the release of egg during ovulation. Further, HCG can be used to stimulate ovulation and address infertility in women.
If you’re confused what HCG has to do among men, then continue reading.
HCG therapy is given among young boys when their testicles didn’t go down in their scrotum as it should be. HCG is also important in preventing testicular shrinkage when using testosterone or anabolic steroid for a long time.
Once testosterone is replaced, it stimulates the production of gonadotropin releasing hormone (GnRH). When GnRH isn’t present, the release of luteinizing hormone is halted by the pituitary gland. Without LH, the testicles couldn’t produce testosterone for the body. A decrease in testosterone can cause testicular shrinkage but once they are replaced, they start to enlarge again and immediately produce testosterone when HCG therapy is administered. HCG Therapy enhances a man’s testes in producing more testosterone.
HCG, when administered in small doses two to three times a week with testosterone replacement, can treat the reduced level of intratesticular testosterone. HCG is believed to have an LH-mimicking action, as well as the increase in the production of intratesticular testosterone. This is one of the reasons why many men are able to keep their fertility and libido when using 500 IU of HCG therapy with testosterone.
According to recent studies, it is now possible to maintain normal quality of sperm using the above ways without using FSH (follicle-stimulating hormone). Gonadotropin shouldn’t be ignored since it is necessary for sperm production.
Human Chorionic Gonadotropic is derived from the pregnant women’s urine or from other genetic modifications. The product is commonly available by prescription in different brand names such as Pregnyl, Profasi, Novarel and Follutein.
HCG comes in the form of a powder contained in a vial of 3,500 IU; 5,000 IU; 11,000 IU and more. It is better to contact a pharmacy and request to make vials for you in various IU amount. The vial comes with a 1 ml of bacteriostatic water as a diluent.
HCG therapy is given as an injection under the skin or into the muscles. However, these two methods are still being debated if which one is better. The number of IUs for every injection varies on the amount of bacteriostatic water added to the powder. Bacteriostatic water is a fluid that contains preservatives. The water is added to the powder to reconstitute it before administration. When refrigerated, it has the ability to preserve the HCG for up to six weeks. It is important that you use ultrafine insulin needle when injecting HCG through the skin.
HCG therapy has been proven as one of the best methods to address testicular shrinkage. When a person’s testes shrink, it can greatly affect his psychological and emotional well-being and thus, having an impact on his sex life. To prevent testicles from shrinking and preserve libido, HCG therapy is one of the best treatment options to consider.
Being a leading provider of low testosterone therapy solutions, we are always looking for newer ways to improve blood testosterone levels for our patients. We believe on improving testosterone levels with not only different testosterone treatment options that we offer, but also with diet, exercise, and therapeutic methods. Over the years, we have seen that our patients have greatly benefited from our Low-T therapy and treatment solutions, and our network of patients have grown across across all major cities of United States, including: Los Angeles, Houston, Miami, Chicago, Jersey City, and Seattle.
If you or a loved one is dealing with low blood testosterone levels, contact us today to get a free evaluation of your Low-T symptoms and see how our treatment options can help you with your low testosterone.
Sign up today and Get our ebook, ‘Naturally Increase Your Testosterone Levels’ absolutely FREE.
Saleamp Design January 10th, 2017
Posted In: Hormone Replacement
Tags: HCG, HCG therapy, Human Chorionic Gonadotropin, intratesticular testosterone, libido, Luteinizing Hormone, testes, testicular shrinkage, testosterone, testosterone replacement
Testosterone is important as it maintains our physical strength, our focus, and our mood, but do you an idea about testosterone production? How is it made?
It’s not just an academic question. An understanding of how our bodies produce testosterone leads to an understanding of what might cause our bodies to stop producing enough of the stuff, and understanding a problem is the first step to solving it.
In essence, testosterone is a steroid hormone. The changes and benefits it triggers in the body are detailed right over here. The average male human creates 7mg of testosterone per day, but there are actually three different types. Not all of it is usable by the body, or at least not to produce the effects you’re probably looking for.
Free testosterone is so named because it has no attached proteins. It’s free to float through the bloodstream, and isn’t bonded to any other molecules. Free testosterone is the type of testosterone that has all those great physical and mental benefits, because it’s able to roam our bodies and activate receptors in various cells. Even though this is the kind of testosterone we think of as the most beneficial, it has the smallest concentration of the three. It only comprises about 2%-3% of our total testosterone levels. Everything we do for testosterone production is really meant to increase free testosterone, but the best way to do that is to raise our overall levels.
This type of the male hormone makes up about 40%-50% of our total testosterone levels. It’s bound to SHBG (sex hormone-binding-globulin), which is a protein produced in the liver. It regulates the amount of free testosterone in the body. SHBG-Bound Testosterone is what’s known as “biologically inactive”, meaning it doesn’t actually have any other effect in our bodies beyond helping regulate our total levels. This type of T doesn’t have harmful effects either, but it is why a man might test with adequately high testosterone levels but still experience the symptoms of testosterone deficiency.
This makes up the remainder of our total testosterone. It’s bound to the protein albumin, which is also produced in the liver. Its function is to stabilize fluid volumes between our cells. Albumin-Bound Testosterone is also biologically inactive, but unlike the SHBG-Bound variety, its bond can be broken. That converts it back into free testosterone, making the stuff sort of testosterone reserve supply.
About 95% of our testosterone is produced in the testicles. The rest is made in our adrenal glands, which is why the hormone is present in women as well. For men, though, it’s almost entirely the testicles.
It’s a pretty complex process that results in the male hormone. Learn about testosterone production in this basic rundown:
The hypothalamus (part of the brain) secretes gonadotropin-releasing hormone. This stuff loops around to the back of the brain and hits the pituitary gland.
The pituitary gland receives the gonadotropin-releasing hormone, and responds by producing two more hormones. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Both of these natural chemicals enter the bloodstream and make their way to the testicles.
Once they’ve arrived down there, the FSH and LH do two different things. FSH initiates sperm production (important!), while LH kicks off testosterone production (just as important!)
The actual cells that create the testosterone are called Leydig cells. They work by converting cholesterol into testosterone. That cholesterol literally comes from the bloodstream, which is why a healthy level of T can actually improve your heart health. It’s also the reason eating eggs is so beneficial to testosterone levels!
During testosterone production, it’s released by the testicles into the bloodstream. Most of the stuff attaches to SHBG and albumin, nullifying its effects. It’s the small amount that remains free that aids our strength, focus, sexual drive, and all the other great benefits of testosterone.
Here’s a handy chart of the HPA-axis:
In essence, testosterone is a steroid hormone. The changes and benefits it triggers in the body are detailed right over here. The average male human creates 7mg of testosterone per day, but there are actually three different types. Not all of it is usable by the body, or at least not to produce the effects you’re probably looking for.
Hormone Therapeutics aims to help people looking to improve and optimize their health through natural means or through the guidance of our physicians.
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Saleamp Design November 4th, 2016
Posted In: Low T Info
Tags: albumin, biologically available, Follicle Stimulating Hormone, free testosterone, FSH, GnRH, growth hormone, HPA axis, hypothalamus, LH, low t, Luteinizing Hormone, pituitary, sex hormone-binding-globulin, SHBG, testicles, testosterone, testosterone levels, testosterone production